Is PT-141 the same as bremelanotide?

Yes. PT-141 is the development code; bremelanotide is the INN; Vyleesi is the commercial brand.

What's the FDA-approved dose?

1.75 mg subcutaneous, taken at least 45 minutes before anticipated sexual activity, no more than once per 24 hours and no more than 8 doses per month.

PT-141 Calculator

PT-141 (also known as Bremelanotide) reconstitution and dosage reference — calculate vial concentration, BAC water volume, and exact syringe units below.

Also known as: Bremelanotide, Vyleesi

Sexual

Key takeaways

At the reference preset of a 10mg PT-141 vial reconstituted with 2 mL of bacteriostatic water, a 1.75mg dose measures 35 units on a U-100 insulin syringe.

PT-141 (bremelanotide) is a melanocortin receptor agonist FDA-approved as Vyleesi for acquired hypoactive sexual desire disorder in premenopausal women at a 1.75 mg subcutaneous dose.

Concentration: 5 mg/mL
Draw volume: 0.35 mL
Units (U-100): 35
Doses per vial: ≈ 5
Reference preset: 10mg · 2mL · 1.75mg

Reference values from the default preset — adjust the calculator below for your vial.

U-100 scale · draw to 35 units

How to use this calculator›

1. Vial — the peptide amount printed on the vial, in milligrams.
2. BAC water — the bacteriostatic water added to the vial. More water means a lower concentration and a larger, easier-to-read draw.
3. Dose — the single dose being measured, in milligrams.
4. Syringe — the barrel being drawn into. The diagram rescales to that syringe, so the same dose sits at a different mark on a 0.3 mL barrel than on a U-100.

Educational reference only — not medical advice or a dosing recommendation.

Default: 10mg / 2mL / 1.75mgAdjust inputs to match your vial

About

What is PT-141?

PT-141 (bremelanotide) is a melanocortin receptor agonist FDA-approved as Vyleesi for acquired hypoactive sexual desire disorder in premenopausal women at a 1.75 mg subcutaneous dose. Off-label use in men for erectile function is widespread but not FDA-approved.

Sourcing

Where researchers source this

Vendors below have been manually vetted for third-party COA practice and shipping reliability. Verify the current Certificate of Analysis on the vendor's product page before purchase.

Ascension Peptides

USA-based research vendor (Castle Rock, Colorado) publishing a per-batch Certificate of Analysis library with public lot IDs, so a vial can be matched to its own COA before and after purchase. Recent HPLC purity 99.79–99.98% across the catalog. Ships from the US and carries the full GLP-1 reference range alongside repair, longevity and cosmetic compounds.

Buy PT-141 10mg →

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Common vial sizes

5 mg	lyophilized powder
10 mg	lyophilized powder

Reference dose ranges

0.5 mg	≈ 10 U-100 units (at 10mg / 2mL)
1 mg	≈ 20 U-100 units (at 10mg / 2mL)
1.75 mg	≈ 35 U-100 units (at 10mg / 2mL)
2 mg	≈ 40 U-100 units (at 10mg / 2mL)

Reconstitution

How it's typically prepared

Reconstitute with BAC water; refrigerate.

FAQ

Frequently asked questions

Is PT-141 the same as bremelanotide?: Yes. PT-141 is the development code; bremelanotide is the INN; Vyleesi is the commercial brand.
What's the FDA-approved dose?: 1.75 mg subcutaneous, taken at least 45 minutes before anticipated sexual activity, no more than once per 24 hours and no more than 8 doses per month.

Sources

References

Other Sexual peptides

Notice

PeptideDose is an educational reference. It is not medical advice and does not replace consultation with a licensed healthcare provider. Doses shown in presets are derived from published protocols and product labels — they are not personal recommendations.