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Peptide unit converters.

Mass-to-activity converters for peptides labelled in International Units. These pages handle the IU-to-mg ratios that come from biological-activity standards — a different arithmetic from the vial-to-syringe math handled by the reconstitution calculator.

About unit conversions

Why mg and IU disagree, and which one your vial uses

Most research peptides are quantified in milligrams — a direct mass measurement that comes off a balance and lines up with how the powder is weighed during compounding. A handful of compounds are quantified in International Units instead. International Units are a biological-activity unit: an IU is defined against a reference preparation with a stated effect at the receptor, so the value tracks expected pharmacological response rather than raw molecular weight. Somatropin and HCG are the most common IU-labelled peptides on this site; insulin is the third historical example and is referenced in some related calculations.

For somatropin specifically, the WHO reference standard fixes the conversion at approximately 3 IU per milligram, so a 10 IU vial corresponds to roughly 3.33 mg of recombinant human growth hormone. Different brands — Genotropin, Humatrope, Norditropin, Saizen, Omnitrope — print the IU value on the carton because that is how clinical doses are written, even when an underlying mg specification exists. Compounded research-grade vials sometimes invert the convention and print mg, which is why a converter is useful: the protocol you are following may state one unit while the vial in front of you uses the other.

The two converters below cover both directions. Each page renders a static lookup table so the value can be checked without typing into a calculator, plus a worked example for the most commonly bought vial sizes. The arithmetic is intentionally transparent — the math is the same 1 mg = 3 IU constant applied across a range, not a black-box transformation.

FAQ

Frequently asked questions about unit conversions

Why are some peptides labelled in IU instead of mg?
International Units measure biological activity rather than mass. For compounds where the active conformation matters as much as the raw protein weight — somatropin, HCG, insulin — historical reference standards fixed an IU value that maps to an expected receptor-level effect. Mass-based labelling was added later, which is why a single vial can carry both "10 IU" and "3.33 mg" on its packaging. The IU-to-mg ratio is compound-specific; somatropin is the canonical 1 mg ≈ 3 IU case, while HCG uses a different activity standard.
Are these converters the same as the reconstitution calculator?
No — they answer different questions. The unit converters on this page handle the static activity-to-mass ratio printed on a vial. The reconstitution calculator under /calculator handles the dynamic vial-size × BAC-water × dose math that decides how many U-100 insulin-syringe units a given dose requires. You typically use a unit converter once (to interpret a label) and the reconstitution calculator every time you draw a syringe.
Is the 1 mg = 3 IU somatropin ratio exact?
It is a clinical convention rooted in the WHO somatropin reference standard, not a precise physical-chemistry constant. Recombinant batches typically test between 2.9 and 3.1 IU per mg of pure protein. Pharmacy labelling rounds to exactly 3 for practical dosing, so a 10 IU vial is treated as 3.33 mg even though the actual mass may differ by a percent or two. The converters on this page use the labelling convention.
Notice

PeptideDose is an educational reference. It is not medical advice and does not replace consultation with a licensed healthcare provider. Doses shown in presets are derived from published protocols and product labels — they are not personal recommendations.