Is IGF-1 LR3 the same as IGF-1?

No — LR3 is an engineered long-acting analogue. Native IGF-1 has a much shorter half-life.

IGF-1 LR3 Calculator

IGF-1 LR3 (also known as Long R3 IGF-1) reconstitution and dosage reference — calculate vial concentration, BAC water volume, and exact syringe units below.

GHS

Key takeaways

At the reference preset of a 1mg IGF-1 LR3 vial reconstituted with 1 mL of bacteriostatic water, a 0.05mg dose measures 5 units on a U-100 insulin syringe.

IGF-1 LR3 is a 83-amino-acid analogue of insulin-like growth factor 1 with an extended N-terminus and Arg3 substitution that gives it a longer half-life and weaker binding to IGF-binding proteins.

Concentration: 1 mg/mL
Draw volume: 0.05 mL
Units (U-100): 5
Doses per vial: ≈ 20
Reference preset: 1mg · 1mL · 0.05mg

U-100 scale · draw to 5 units

Reference values from the default preset — adjust the calculator below for your vial.

Default: 1mg / 1mL / 0.05mgAdjust inputs to match your vial

HGH (Somatropin) calculator →Norditropin FlexPro →

About

What is IGF-1 LR3?

IGF-1 LR3 is a 83-amino-acid analogue of insulin-like growth factor 1 with an extended N-terminus and Arg3 substitution that gives it a longer half-life and weaker binding to IGF-binding proteins. Used in research and bodybuilding contexts; safety profile in humans is poorly characterized.

Common vial sizes

1 mg	lyophilized powder
5 mg	lyophilized powder

Reference dose ranges

0.02 mg	≈ 2 U-100 units (at 1mg / 1mL)
0.05 mg	≈ 5 U-100 units (at 1mg / 1mL)
0.1 mg	≈ 10 U-100 units (at 1mg / 1mL)

Reconstitution

How it's typically prepared

Reconstitute with BAC water; refrigerate. IGF-1 LR3 is potent — start low.

FAQ

Frequently asked questions

Is IGF-1 LR3 the same as IGF-1?: No — LR3 is an engineered long-acting analogue. Native IGF-1 has a much shorter half-life.

Sources

References

PubMed search: IGF-1 LR3

Sourcing

Where researchers source this

Vendors below have been manually vetted for third-party COA practice and shipping reliability. Verify the current Certificate of Analysis on the vendor's product page before purchase.

Apollo Peptide Sciences

USA-based research vendor with third-party HPLC and mass spectrometry COAs plus endotoxin reports published per product. Specialty in GLP-1 reference compounds (Semaglutide, Tirzepatide, Retatrutide). Ships within 48 hours via USPS Priority/Express. 120-day cookie window — the longest US attribution in the space.

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HGH (Somatropin) — IU dosing reference and reconstitution chart.

Notice

PeptideDose is an educational reference. It is not medical advice and does not replace consultation with a licensed healthcare provider. Doses shown in presets are derived from published protocols and product labels — they are not personal recommendations.