GHRP / GHRH Stack

CJC-1295 + Ipamorelin

The CJC-1295 + ipamorelin combination is the most widely used growth-hormone-axis stack. CJC-1295 is a GHRH analogue; ipamorelin is a selective GH secretagogue. Co-administration produces a synergistic GH pulse larger than either component alone.

Calculator

Compute a dose for any component

Switch between stack members using the chip strip. Each is preset to a typical vial and dose.

Rationale

Why these peptides together

GHRH (CJC-1295) and a ghrelin agonist (ipamorelin) act on different pituitary pathways. Co-stimulation typically produces a 2–3× GH pulse compared with either agent alone, while ipamorelin's selectivity keeps cortisol and prolactin near baseline.

Protocol notes

How it's typically run

Reconstituted in either separate vials or as a co-formulated blend. Typical research protocol: 100 µg ipamorelin + 100 µg Mod-GRF 1-29 (or weekly CJC-1295 with DAC at 1–2 mg) two to three times daily, often timed pre-bed and post-workout.

FAQ

Frequently asked questions

Why combine CJC-1295 with ipamorelin?
GHRH analogues and GH secretagogues act on different receptors and produce a larger combined GH pulse than either alone — without significantly raising cortisol or prolactin (unlike GHRP-2 or GHRP-6).
DAC or no DAC?
CJC-1295 with DAC has a half-life of ~6–8 days and is dosed weekly. Without DAC (Mod-GRF 1-29) has a 30-minute half-life and preserves a pulsatile profile when dosed multiple times daily.
Notice

PeptideDose is an educational reference. It is not medical advice and does not replace consultation with a licensed healthcare provider. Doses shown in presets are derived from published protocols and product labels — they are not personal recommendations.