Ipamorelin Calculator
What is Ipamorelin?
Ipamorelin is a synthetic pentapeptide growth hormone secretagogue that selectively activates the ghrelin receptor (GHS-R1a) to trigger pituitary GH release. Its defining feature is selectivity: unlike earlier GHRPs such as GHRP-2 and GHRP-6, ipamorelin produces minimal effect on cortisol, prolactin, or aldosterone secretion at typical research doses. Because the GH pulse it generates is short and pulsatile, ipamorelin is most often paired with a GHRH analogue — sermorelin, CJC-1295, or modified GRF(1-29) — in research protocols. The two-compound combination produces a synergistic GH peak that more closely resembles physiological GH pulsatility than either compound alone. Ipamorelin is not FDA-approved for any indication and remains a research-only compound; published clinical investigation has been limited.
| 2 mg | lyophilized powder |
| 5 mg | lyophilized powder |
| 10 mg | lyophilized powder |
| 0.1 mg | ≈ 4 U-100 units (at 5mg / 2mL) |
| 0.2 mg | ≈ 8 U-100 units (at 5mg / 2mL) |
| 0.3 mg | ≈ 12 U-100 units (at 5mg / 2mL) |
How it's typically prepared
Reconstitute with bacteriostatic water and store refrigerated at 2–8 °C. The lyophilized powder is stable for years at –20 °C; reconstituted solution is typically used within 2–4 weeks. Subcutaneous injection with a U-100 insulin syringe is the most common research route. Ipamorelin is sometimes co-formulated with CJC-1295 in a single vial — verify which is the case before drawing.
Frequently asked questions
- Why is ipamorelin preferred over GHRP-2 or GHRP-6?
- Ipamorelin is more selective and does not appreciably raise cortisol or prolactin, which makes it the most commonly chosen GH secretagogue in current research literature.
- Is ipamorelin FDA-approved?
- No. Ipamorelin is not FDA-approved for any indication. It is researched as a tool compound in GH-axis studies and is sometimes compounded by US compounding pharmacies, though its compounded status has been challenged by FDA in recent guidance.
- What is the typical ipamorelin dose used in research protocols?
- Reported research doses range from 100 to 300 µg per administration, two to three times daily. The calculator above renders the equivalent insulin-syringe units at the most common reconstitution ratios.
- Does ipamorelin work better alone or paired with CJC-1295?
- GHRH-analogue / GHS combinations produce a larger GH pulse than either compound alone in published studies — this is why most research protocols use ipamorelin with sermorelin, CJC-1295, or modified GRF(1-29) rather than as a monotherapy.
- What is the half-life of ipamorelin?
- Approximately 2 hours in plasma, which is why dosing is typically repeated multiple times per day rather than given as a single daily injection.
- Why is ipamorelin given multiple times per day?
- Endogenous GH release is pulsatile, with multiple peaks across a 24-hour period. Multi-daily ipamorelin administration approximates this pattern more closely than once-daily dosing.
Where researchers source this
Vendors below have been manually vetted for third-party COA practice and shipping reliability. Verify the current Certificate of Analysis on the vendor's product page before purchase.
Apollo Peptide SciencesUSA-based research vendor with third-party HPLC and mass spectrometry COAs plus endotoxin reports published per product. Specialty in GLP-1 reference compounds (Semaglutide, Tirzepatide, Retatrutide). Ships within 48 hours via USPS Priority/Express. 120-day cookie window — the longest US attribution in the space.
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EU-based vendor (Slovakia, since 2015) shipping to EU, UK, and Switzerland. The only European supplier publishing all seven test parameters per batch (purity, identity, content, bioburden, endotoxins, heavy metals class 1 & 2). Manufacturer is cGMP / ISO 9001 / ISO 13485 compliant.
Buy Ipamorelin 5mg →Affiliate link — we may earn a commission at no extra cost to you.
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PeptideDose is an educational reference. It is not medical advice and does not replace consultation with a licensed healthcare provider. Doses shown in presets are derived from published protocols and product labels — they are not personal recommendations.